Twenty subfractions obtained by high-performance gel permeation chromatography for detecting icodextrin dialysate improve atherogenic lipoprotein profiles in peritoneal dialysis patients
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Relationship between Icodextrin use and decreased level of small low-density lipoprotein cholesterol fractioned by high-performance gel permeation chromatography
BACKGROUND Because of the absorption of glucose in peritoneal dialysis (PD) solution, PD patients show an atherogenic lipid profile, which is predictive of poor survival in PD patients. Lipoprotein subclasses consist of a continuous spectrum of particles of different sizes and densities (fraction). In this study, we investigated the lipoprotein fractions in PD patients with controlled serum low...
متن کاملIcodextrin instead of glucose during the daytime dwell in CCPD increases ultrafiltration and 24-h dialysate creatinine clearance.
BACKGROUND AND METHODS Icodextrin 7.5% is an iso-osmolar, glucose polymer-containing peritoneal dialysis solution with an ultrafiltration potential similar to glucose 3.86%. We compared in an open, randomized, prospective study the ultrafiltration potential of icodextrin with that of glucose during the daytime dwell of 23 patients treated with automated peritoneal dialysis (CCPD). RESULTS Day...
متن کاملPortable or wearable peritoneal devices--the next step forward for peritoneal dialysis?
Peritoneal dialysis can be considered a "wearable" dialysis therapy. However, patients typically require 3 or 4 daily exchanges, each taking 20-40 minutes and potentially increasing the risk of infection by repeated disconnection and reconnection. Although peritoneal dialysis cyclers allow patients to be "free" from their machine for 13-15 hours, they similarly need a supply of fresh dialysate....
متن کاملLong daytime exchange in children on continuous cycling peritoneal dialysis: preservation of drained volume because of icodextrin use.
Daytime exchanges with glucose osmotic agents often lead to dialysate reabsorption, poor ultrafiltration (UF), positive sodium balance, and restricted purification of uremic toxins. We studied 5 anuric children on continuous cycling peritoneal dialysis (mean age: 10 years, 10 months), comparing icodextrin to a conventional glucose-based dialysate. The same fill volume (980 +/- 290 mL/m2) and th...
متن کاملSafety Issues of Long-Term Glucose Load in Patients on Peritoneal Dialysis—A 7-Year Cohort Study
BACKGROUND Effects of long-term glucose load on peritoneal dialysis (PD) patient safety and outcomes have seldom been reported. This study demonstrates the influence of long-term glucose load on patient and technique survival. METHODS We surveyed 173 incident PD patients. Long-term glucose load was evaluated by calculating the average dialysate glucose concentration since initiation of PD. Ri...
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تاریخ انتشار 2013